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找到约 33 条 “Antagonist G” 相关结果（用时 0.074 秒）

目录号	产品名称	中文名称	靶点
M9082	ISO-1	ISO-1	NLR
	MIF Antagonist; Macrophage Migration Inhibitory Factor
	ISO-1是一种有效的巨噬细胞迁移抑制因子MIF的抑制剂，IC50值为6.2 ± 3.8 μM，可以通过降低血脑屏障(BBB)的通透性来保护神经元。此外，ISO-1还可减少NLRP3、ASC、caspase-1和IL-1β的蛋白表达，以及MIF、IL-6、TNF-α、IL-1β和IL-18的mRNA表达，可用于癌症的相关研究。
M10242	Antagonist G	Antagonist G	Vasopressin Receptor
	ARG-D-TRP-N-ME-PHE-D-TRP-LEU-MET-NH2
	Antagonist G是一个多肽，也是一种有效的vasopressin受体拮抗剂。
M41342	FKBP51F67V-selective antagonist Ligand2	FKBP51F67V-selective antagonist Ligand2	FKBP (FK506-binding protein)
	FKBP51F67V-selective antagonist Ligand2 是一种有效的 FKBP51 F67V-选择性拮抗剂配体。
M2584	MDL-29951	MDL-29951	GluR
	MDL-29951 is a novel glycine antagonist of NMDA receptor activation (Ki=0.14 mM, [3H]glycine binding) in vitro and in vivo with IC50 value of 0.14 mM ([3H]glycine binding).
M2947	Pipenzolate Bromide	溴哌喷酯	AChR/AChE
	Pipenzolate is an antimuscarinic, which binds to muscarinic receptors as an antagonist therefore preventing acetyl choline from binding to the receptors.
M9742	CU-CPT-9a	CU-CPT-9a	TLR
	CU-CPT-9a is a potent TLR8 antagonist with IC50 of 0.5 nM, which that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells.
M5076	ZK200775 hydrate	ZK200775 hydrate	GluR
	Fanapanel; MPQX
	ZK200775 hydrate is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively.
M5920	Ramosetron HCl	盐酸雷莫司琼	5-HT Receptor
	YM060
	Ramosetron Hydrochloride (盐酸雷莫司琼; YM060 Hydrochloride) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting.
M6471	Astemizole	阿司咪唑	Histamine Receptor
	Astemizole is a orally active, potent H ₁ antagonist. Also K _V11.1 (hERG) channel blocker.
M6639	Cyanopindolol hemifumarate	Cyanopindolol hemifumarate	Others
	Cyanopindolol hemifumarate is a 5-HT1A/1B antagonist with roughly equal affinity at each receptor; also a β-adrenoceptor antagonist.
M6774	GSK 789472 hydrochloride	GSK 789472 hydrochloride	Others
	GSK 789472 hydrochloride is a d ₃ antagonist. Also D ₂ partial agonist.
M6818	Ifenprodil hemitartrate	艾芬地尔	Others
	Ifenprodil hemitartrate is a non-competitive NMDA antagonist. Also σ ligand.
M6950	Mesulergine hydrochloride	Mesulergine hydrochloride	Others
	Mesulergine hydrochloride is a 5-HT _2A and 5-HT _2C antagonist. Also dopamine receptor partial agonist.
M7050	NS 3763	NS 3763	Others
	NS 3763 is a selective non-competitive kainate antagonist; selective for GLU _K5.
M7142	PIT 1	PIT 1	Others
	PIT 1 is a pIP ₃ antagonist. Blocks PIP ₃-PH interaction; inhibits Akt signaling.
M7147	PMPA (NMDA antagonist)	PMPA (NMDA antagonist)	Others
	PMPA (NMDA antagonist) is a competitive NMDA antagonist.
M7168	PSB 10 hydrochloride	PSB 10 hydrochloride	Others
	PSB 10 hydrochloride is a potent, highly selective hA ₃ receptor antagonist/inverse agonist.
M7259	SB 228357	SB 228357	5-HT Receptor
	SB 228357 is a 5-HT _2C/2B antagonist/inverse agonist.
M7283	SDM25N hydrochloride	SDM25N hydrochloride	Others
	SDM25N hydrochloride is a potent, selective non-peptide δ antagonist; also inhibits dengue virus replication.
M7294	SIB 1893	SIB 1893	GluR
	SIB 1893 is a mGlu ₅ antagonist and positive allosteric modulator at mGlu ₄.
M7320	Spiperone hydrochloride	螺哌隆盐酸盐	Others
	Spiperone hydrochloride is a 5-HT _2A antagonist. Also D ₂-like antagonist.
M7411	threo Ifenprodil hemitartrate	threo Ifenprodil hemitartrate	Others
	threo Ifenprodil hemitartrate is a nR2B-selective NMDA antagonist; also σ agonist.
M7445	UBP 282	UBP 282	Others
	UBP 282 is a aMPA/kainate antagonist; distinguishes between motoneuron and dorsal root kainate receptors.
M7608	AH23848 hemicalcium salt	AH23848 hemicalcium salt	Others
	EP₄ prostanoid receptor antagonist with TP blocking activity.
M7695	CGS-9343B	CGS-9343B	Others
	CGS-9343B is a selective calmodulin antagonist with minimal protein kinase C or antidopaminergic activity.
M7697	Chlorprothixene hydrochloride	盐酸氯普噻吨	Others
	D₂ dopamine receptor antagonist; blocks a subset of GABA_A receptors in rat cortex that is also blocked by clozapine; thioxanthine antipsychotic.
M7783	Efaroxan hydrochloride	依法克生	Others
	(+)-Isomer is a selective α-adrenoceptor antagonist; (−)-isomer is an imidazoline ligand that induces insulin secretion, mediated by the blockade of ATP-sensitive potassium channels in pancreatic β cells; I₁ imidazoline binding site antagonist.
M7859	Idazoxan hydrochloride	盐酸咪唑克生	Others
	α₂-adrenoceptor antagonist; I₂ imidazoline receptor agonist; I₁ imidazoline receptor antagonist.
M7888	Levocabastine hydrochloride	左旋多巴	Others
	Non-peptide histamine H₁receptor antagonist; neurotensin NTS₂ receptor ligand.
M7903	Metaphit methanesulfonate salt	蛋氨酸甲烷盐	Sigma Receptor
	Metaphit methanesulfonate salt is an irreversible, non-competitive antagonist at the phencyclidine site on the NMDA receptor; sigma receptor irreversible, competitive antagonist.
M7915	MRS 1191	MRS 1191	Others
	MRS 1191 is putative A3 adenosine receptor antagonist, highly selective for human A3 receptor vs human A1 receptor.
M7920	MMPIP	MMPIP	Others
	MMPIP is a potent, selective, allosteric antagonist of metabotropic glutamate receptor 7 (mGluR7).
M7932	MRS 2395	MRS 2395	Others
	Antagonist for P2Y₁₂ purinoceptor; inhibits ADP-induced aggregation in rat platelets and antagonizes ADP-induced inhibition of cAMP in rat and human platelets in the presence of PGE1.

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